Actively Recruiting
The Benefits of Continued Use of Ovarian Function Suppression After 5 Years
Led by Hongmei Zheng, PhD · Updated on 2025-03-17
1200
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To observe and evaluate the clinical efficacy and safety of continuous use of OFS for premenopausal patients with early breast cancer after 5 years use of OFS. This study is a multicenter, prospective, observational, non randomized controlled, open-label real world study based on hospital medical record system data, aimed at evaluating the benefits of continuing to use OFS after 5 years of use. The retrospective analysis plan includes patient data from September 1, 2023 to September 1, 2026. Join two cohorts: the continued use group and the discontinued use group after 5 years of OFS, respectively.
CONDITIONS
Official Title
The Benefits of Continued Use of Ovarian Function Suppression After 5 Years
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with early primary breast cancer
- Female aged 18-60 years (including 18 and 60 years)
- Hormone receptor (HR) positive and HER2 negative breast cancer
- Completed 5 years of ovarian function suppression treatment
- ECOG performance status score of 0 or 1
- Voluntarily agree to join the study and sign informed consent
- Considered by the researcher to potentially benefit from the study
You will not qualify if you...
- Receiving treatments that affect ovarian function suppression simultaneously
- Received ovarian function suppression treatment for less than 5 years
- Have symptomatic central nervous system metastases such as headache, cerebral edema, or blurred vision
- Have symptomatic invasive metastases
- Considered unsuitable for inclusion by the doctor
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Wu Xinhong
Wuhan, Hubei, China
Actively Recruiting
Research Team
H
Hongmei Zheng, Doctor
CONTACT
X
Xinhong Wu, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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