Actively Recruiting
Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis
Led by Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta · Updated on 2024-07-03
57
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
Sponsors
I
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Lead Sponsor
U
University Hospital of Girona Dr. Josep Trueta
Collaborating Sponsor
AI-Summary
What this Trial Is About
Bronchiectasis is a chronic bronchial disease in which the usual capacity to remove secretions does not function correctly, causing mucus retention that leads to chronic infection. As with all infections, the use of antibiotics and puss removal are essential treatment elements. Physiotherapeutic techniques are used to assist in the removal of secretions, although these are time-consuming practices that need to be much better studied and which patients often do not continue practicing diligently. A physiotherapeutic technique called (Slow prolonged expiration in lateral decubitus) ELTGOL has been shown to be somewhat effective but as the mucus is viscous in this disorder, it can be difficult to get it to move. It is thought that saline solution inhalations may reduce mucus viscosity and could help to ease expectoration, facilitating the removal of the mucus by the physiotherapeutic technique. This project aims to test this hypothesis, which if true could represent an advance in the treatment of this severely debilitating disease.
CONDITIONS
Official Title
Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients with bronchiectasis confirmed by high resolution computed tomography
- No exacerbations in the previous month
- Chronic mucopurulent and purulent sputum
- 10ml daily expectoration
- At least one exacerbation in the previous year
- Forced expiratory volume the 1st second (FEV1) 30% after bronchodilation
- Signed informed consent
You will not qualify if you...
- Current smokers or a smoking history of 20 pack-years
- Asthma, allergic bronchopulmonary aspergillosis or cystic fibrosis
- Pregnant or lactating women
- Use of mucoactive treatment in the previous month
- Inability to perform ELTGOL, spirometry, or attend visits
- Participation in pulmonary rehabilitation in the previous 6 months
- Change of treatment in the previous month
- Uncontrolled hypertension
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Girona Dr. Josep Trueta
Girona, Spain
Actively Recruiting
Research Team
G
Gerard Muñoz, PhD PT
CONTACT
N
Neus Puigdevall, PT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here