Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT03860233

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Led by Vivek Jain · Updated on 2026-05-04

40

Participants Needed

1

Research Sites

408 weeks

Total Duration

On this page

Sponsors

V

Vivek Jain

Lead Sponsor

G

George Washington University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will investigate if an intra-nasal nose spray of the drug oxytocin can decrease the amount of pressure needed from the automatic Continuous Positive Airway Pressure (CPAP) device while sleeping decreasing some of the harmful effects of low oxygen in people with sleep apnea. This study will last 35 nights and involves spending three nights in the sleep lab at George Washington University. There are no additional costs to participants and no compensation for being involved in the study.

CONDITIONS

Official Title

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men or women 18 years of age or older.
Not Eligible

You will not qualify if you...

  • Subjects not willing or unable to use CPAP for treatment of obstructive sleep apnea.
  • Presence of other sleep disorders.
  • Pregnant or breastfeeding women.
  • Women of child-bearing age not willing or unable to use an accepted method to avoid pregnancy during the study.
  • Prisoners or individuals involuntarily incarcerated.
  • Subjects compulsorily detained or treated for psychiatric or physical illness.
  • Patients unable to give consent due to language barrier or other reasons.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Medical Faculty Associates

Washington D.C., District of Columbia, United States, 20037

Actively Recruiting

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Research Team

V

Vivek Jain, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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