Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06569212

Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS)

Led by Madeleine Puissant · Updated on 2024-11-26

20

Participants Needed

1

Research Sites

257 weeks

Total Duration

On this page

Sponsors

M

Madeleine Puissant

Lead Sponsor

M

MaineHealth

Collaborating Sponsor

AI-Summary

What this Trial Is About

To determine the effect of early metoprolol administration after non-traumatic subarachnoid hemorrhage (SAH).

CONDITIONS

Official Title

Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Older than 18 years of age
  • Neuro-imaging confirmed non-traumatic subarachnoid hemorrhage
Not Eligible

You will not qualify if you...

  • Traumatic cause of subarachnoid hemorrhage such as fall, motor vehicle accident, or other blunt trauma
  • Other types of intracranial bleeding including intracerebral hemorrhage, subdural hemorrhage, or epidural hemorrhage
  • Pregnancy
  • Unstable vital signs not suitable for beta-1 adrenergic receptor inhibitor treatment including systolic blood pressure below 80 mmHg not stabilized by medications, heart rate below 50 beats per minute with low blood pressure, or need for vasopressor agents due to hypotension
  • Any other vital sign concerns as determined by the treatment team
  • History of severe heart failure (Stage C or D or NYHA Class III or IV)
  • Unwillingness or inability of patient or legal representative to provide informed consent

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

MaineHealth

Portland, Maine, United States, 04012

Actively Recruiting

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Research Team

M

Madeleine Puissant, MD, PhD

CONTACT

C

Christine Lord

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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