Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT05018221

Better Evidence and Translation for Calciphylaxis

Led by University of Sydney · Updated on 2025-08-13

350

Participants Needed

21

Research Sites

431 weeks

Total Duration

On this page

Sponsors

U

University of Sydney

Lead Sponsor

A

Australasian Kidney Trials Network

Collaborating Sponsor

AI-Summary

What this Trial Is About

This global platform study will evaluate multiple interventions, across several domains of therapeutic care, in adult patients with kidney failure and newly diagnosed calciphylaxis.

CONDITIONS

Official Title

Better Evidence and Translation for Calciphylaxis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Currently receiving hemodialysis or peritoneal dialysis that can be converted to hemodialysis, with plans for ongoing hemodialysis at least three times per week during the study treatments
  • Have a new calciphylaxis ulcer present for less than 10 weeks
  • Age 18 years or older
  • Eligible for randomization in at least one recruiting treatment area
  • Participant and treating physician willing and able to carry out trial procedures
Not Eligible

You will not qualify if you...

  • None

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 21 locations

1

Concord Repatriation General Hospital

Concord, New South Wales, Australia

Actively Recruiting

2

St George Hospital

Kogarah, New South Wales, Australia

Actively Recruiting

3

Liverpool Hospital

Liverpool, New South Wales, Australia, 2170

Actively Recruiting

4

John Hunter Hospital

New Lambton Heights, New South Wales, Australia, 2305

Actively Recruiting

5

Westmead Hospital

Westmead, New South Wales, Australia, 2145

Actively Recruiting

6

Sunshine Coast Hospital and Health Service

Birtinya, Queensland, Australia

Actively Recruiting

7

Princess Alexandra Hospital

Brisbane, Queensland, Australia

Actively Recruiting

8

Bundaberg Base Hospital

Bundaberg, Queensland, Australia

Actively Recruiting

9

Cairns Hospital

Cairns, Queensland, Australia, 4870

Actively Recruiting

10

Townsville Hospital

Douglas, Queensland, Australia, 4814

Actively Recruiting

11

Ipswich Hospital

Ipswich, Queensland, Australia, 4305

Actively Recruiting

12

Royal Melbourne Hospital

Melbourne, Victoria, Australia

Actively Recruiting

13

Sunshine Hospital (Western Health)

St Albans, Victoria, Australia

Actively Recruiting

14

Royal Perth Hospital

Perth, Western Australia, Australia, 6000

Actively Recruiting

15

Royal Adelaide Hospital

Adelaide, Australia

Actively Recruiting

16

Monash Medical Centre

Clayton, Australia

Actively Recruiting

17

Dunedin Hospital

Dunedin, New Zealand

Actively Recruiting

18

Auckland City Hospital (Auckland DHB)

Grafton, New Zealand

Actively Recruiting

19

North Shore Hospital (Waitemata DHB)

Takapuna, New Zealand

Actively Recruiting

20

Tauranga Hospital

Tauranga, New Zealand

Actively Recruiting

21

Whangarei Hospital

Whangarei, New Zealand

Actively Recruiting

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Research Team

S

Sibyl Masterman

CONTACT

M

Meg Jardine

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

6

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