Actively Recruiting
The Better, Harder, Faster, Stronger Study
Led by Wake Forest University Health Sciences · Updated on 2025-10-24
35
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
A
Atrium Health Wake Forest Baptist
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate changes in the electronic Frailty Index (eFI) score following 3-4 cycles of neoadjuvant chemotherapy (NACT) in participants with advanced ovarian and endometrial cancer.
CONDITIONS
Official Title
The Better, Harder, Faster, Stronger Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and willingness to sign an IRB-approved informed consent.
- Age > 55 years at the time of enrollment.
- Newly diagnosed suspected ovarian/primary peritoneal/fallopian tube carcinoma of any histological subtype, FIGO Stage II-IV, per enrolling investigator, or newly diagnosed suspected endometrial carcinoma of any histologic subtype, FIGO Stage II-IV, per enrolling investigator.
- Planned for 3 or 4 cycles of NACT, with interval cytoreductive surgery planned thereafter.
- Ability to read, understand, and write the English language.
- As determined by the enrolling investigator, ability of the participant to understand and comply with study procedures for the entire length of the study.
You will not qualify if you...
- History of brain metastases.
- History of poorly controlled psychiatric conditions, defined as hospitalization within the prior 3 months for psychiatric disorders, traumatic brain injury, cerebrovascular event, or dementia, per the enrolling investigator.
- Use of anti-amyloid agents, cholinesterase inhibitors, or glutamate regulators at the time of enrollment.
- Vision impairment that would impede completion of study assessments, per enrolling investigator.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, North Carolina, United States, 27157
Actively Recruiting
Research Team
S
Sydney McEntire, RN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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