Actively Recruiting
Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
Led by Endeavor Health · Updated on 2026-03-16
30
Participants Needed
1
Research Sites
133 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy. This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight. Participants will be asked to complete: * MRI in the second trimester (20-24 weeks) * MRI in the third trimester (30-34 weeks)
CONDITIONS
Official Title
Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Singleton pregnancy less than 24 weeks gestation
- Pre-pregnancy BMI between 18.5 and 24.9 kg/m2 or 30 kg/m2 and above
You will not qualify if you...
- Asthma requiring controller medication
- Autoimmune conditions
- Chronic hypertension
- Claustrophobia
- Congenital anomaly
- Pregestational diabetes
- History of bariatric surgery
- HIV infection
- Ineligible for MRI due to incompatible implanted medical device
- Multifetal gestation
- Smoking during pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Endeavor Health
Evanston, Illinois, United States, 60201
Actively Recruiting
Research Team
A
Alexandra Mangus
CONTACT
C
Caitlin A MacGregor, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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