Actively Recruiting
Beyond TME Origins
Led by Imperial College London · Updated on 2024-10-17
383
Participants Needed
4
Research Sites
896 weeks
Total Duration
On this page
Sponsors
I
Imperial College London
Lead Sponsor
P
Pelican Cancer Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available. Patients' recurrence will be staged using our proposed MRI classification. We will be assessing the original primary staging scans and histopathology to learn about risk factors for recurrence. We will record treatment for the recurrence, and patients will be followed up for three years.
CONDITIONS
Official Title
Beyond TME Origins
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Had a primary colorectal adenocarcinoma proven by biopsy taken as part of routine clinical practice
- Has a confirmed diagnosis of recurrent pelvic colorectal cancer
- Has previously completed surgical treatment of primary adenocarcinoma of the colon, sigmoid colon or rectum
- Are able to undergo high resolution MRI for staging prior to treatment decisions
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
You will not qualify if you...
- Have irresectable extra-pelvic metastatic disease
- Original baseline staging and preoperative restaging scans (MR for rectal and sigmoid cancers and/or CT for colon and sigmoid cancers) are unavailable
- Original preoperative, surgical and adjuvant treatment has not been documented or is unavailable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Oslo University Hospital
Oslo, Norway, N-0424
Actively Recruiting
2
St Mark's Hospital
Harrow, London, United Kingdom
Actively Recruiting
3
Churchill Hospital
Oxford, Oxfordshire, United Kingdom
Actively Recruiting
4
Royal Marsden Hospital NHS Foundation Trust
Sutton, United Kingdom, SM2 5PT
Actively Recruiting
Research Team
C
Caroline Martin
CONTACT
S
Syvella Ellis
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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