Actively Recruiting
Effectiveness of Blood Flow Restriction Training on Muscle Morphology and Prevention of Patellofemoral Pain Syndrome and Anterior Cruciate Ligament Injury
Led by Udayana University · Updated on 2025-06-29
75
Participants Needed
1
Research Sites
52 weeks
Total Duration
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AI-Summary
What this Trial Is About
Researchers are evaluating the effects of different exercise training methods on muscle structure and the prevention of Patellofemoral Pain Syndrome and Anterior Cruciate Ligament (ACL) injuries in sportsmen aged 15 to 35 who participate in level 1 sports such as martial arts, basketball, futsal, and soccer. This clinical trial compares low-load blood flow restriction training (LL-BFRt), a sham version of LL-BFRt, and high-load eccentric training (HL-Et) to see which method better improves muscle morphology and reduces injury risk. Participants will be randomly assigned to one of three groups: LL-BFRt, sham LL-BFRt, or HL-Et. The LL-BFRt group will perform eccentric exercises like stairs, single leg squats, and single leg deadlifts at 30% of their maximum repetition and with 70% arterial occlusion pressure applied by cuffs. The sham LL-BFRt group will do the same exercises at 30% maximum repetition but with only 10% arterial occlusion pressure. The HL-Et group will perform the exercises at 70% maximum repetition without blood flow restriction. Both treatments are guided by a physical therapist. Throughout the study, researchers will measure muscle cross-sectional area, fiber angle of the vastus medial obliques, and patella position after 8 weeks. They will also monitor the incidence of Patellofemoral Pain Syndrome and ACL injuries over one year. Participants are expected to maintain their assigned exercise regimen and provide informed consent. The study aims to understand which training method offers better muscle improvements and injury prevention in active sports participants.
CONDITIONS
Brief Title
BFR Training on Muscle Morphology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 15 and 35 years old
- Play level 1 sports such as martial arts, basketball, futsal, or soccer at least twice a week
- Have never experienced Patellofemoral Pain Syndrome or an ACL injury
- Have never had a grade III sprain or strain
- Agree to participate and provide informed consent until the study is completed
You will not qualify if you...
- Have tumor, cancer, blood clots, obesity, diabetes, high blood pressure, anemia, or kidney failure
- Have any disabilities or are disabled
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants complete assigned exercise training programs involving blood flow restriction and eccentric exercises guided by a physical therapist.
Weekly visits for up to 8 weeks
Duration - 1 year
Participants are monitored for the incidence of patellofemoral pain syndrome and anterior cruciate ligament injury.
Periodic assessments during the year following treatment
Trial Site Locations
Total: 1 location
1
Physical therapy laboratory, College of Medicine, Universitas Udayana and ROM Physiotherapy Private Clinic Denpasar
Denpasar, Bali, Indonesia, 80232
Actively Recruiting
Research Team
I
I Putu Gde Surya Adhitya, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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