Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT07045948

Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD

Led by Universitair Ziekenhuis Brussel · Updated on 2025-09-11

100

Participants Needed

1

Research Sites

150 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate how airway inflammation, lung function, and symptoms change over time in people with chronic obstructive pulmonary disease (COPD). Airway inflammation will be assessed using a simple breath test (FeNO) and a small blood sample to measure eosinophils, a type of white blood cell. Participants will be followed for one year, with three study visits (at the start, 6 months, and 12 months). The goal is to understand how these markers evolve and whether they differ between people who experience a worsening of symptoms (called exacerbations) and those who remain stable. All tests except for a small extra blood draw are part of routine COPD care. Participation does not affect standard treatment.

CONDITIONS

Official Title

Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 60 40 years
  • Diagnosed with COPD according to GOLD criteria
  • Attending routine follow-up visits every 6 months
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Recent respiratory tract infection or exacerbation (moderate or severe) within 4 weeks before inclusion
  • Dominant asthmatic phenotype (asthma-COPD overlap with asthma predominance)
  • Severe comorbidities interfering with participation or follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitair Ziekenhuis Brussel

Jette, Belgium, 1090

Actively Recruiting

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Research Team

N

Naomi Michotte, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD | DecenTrialz