International Study on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Stenosis

What this Trial Is About

Researchers are observing patients with bicuspid aortic valve stenosis to understand the outcomes of those undergoing transcatheter aortic valve replacement TAVR. This study aims to evaluate both procedural success and clinical results over time in this patient group. The research is sponsored by Cedars-Sinai Medical Center and focuses on adults diagnosed with severe aortic stenosis and bicuspid valve anatomy who require this intervention. The study involves monitoring patients who have undergone TAVR, a procedure where a device is used to replace the aortic valve through a catheter without open-heart surgery. Participants are selected based on specific clinical criteria, including symptom severity and heart team assessment. This registry does not involve assigning treatments but collects data from patients receiving TAVR as part of their care. Participants will be followed to observe outcomes such as death at multiple time points up to five years after the procedure. Additional measurements include cardiac-related deaths, stroke, hospital readmissions, bleeding, vascular complications, kidney injury, and valve function assessed by echocardiography at discharge and various intervals. The study gathers detailed information to better understand long-term patient results and safety after TAVR in bicuspid aortic valve stenosis.

Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry