Observational Bidirectional Cohort Study of Spondyloarthritis Patients at Nanfang Hospital Tracking Clinical, Laboratory, and Imaging Data During Routine Care

What this Trial Is About

Researchers are collecting detailed information from patients with spondyloarthritis SpA who visit Nanfang Hospital of Southern Medical University. This observational study aims to create a comprehensive disease-specific cohort by recording clinical condition scales, lab results, and imaging data like X-rays and MRIs. The purpose is to build a rich database supporting future research projects, including large-scale and retrospective studies, without adding new treatments or tests beyond routine care. The study gathers two main datasets one on SpA condition information and another on SpA imaging. The condition dataset includes disease duration, symptoms, family history, comorbidities, medication history, and disease activity scores like BASDAI and ASDASCRP. Quality of life and physical function are assessed using scales such as BASFI, EQ-5D, and SF-36. Lab tests recorded include CRP and ESR, but only if prescribed by the usual physician. Imaging data cover various MRIs, CT scans, ultrasounds, and X-rays related to SpA, with scores recorded when available. Participants either provide informed consent for prospective data collection during routine visits every 3 months for the first year and every 6 months for the next three years, totaling four years, or their retrospective data from prior visits are included without new consent if they no longer attend. Researchers monitor disease activity, quality of life, imaging findings, and adverse events throughout. Personal privacy is protected, and no additional interventions are introduced during the follow-up period.

Bidirectional Cohort Study of Nanfang Spondyloarthritis