Actively Recruiting
Bidirectional Cohort Study of Nanfang Spondyloarthritis
Led by Nanfang Hospital, Southern Medical University · Updated on 2025-05-25
3000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
N
Nanfang Hospital, Southern Medical University
Lead Sponsor
S
Southern Medical University, China
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are collecting detailed information from patients with spondyloarthritis (SpA) who visit Nanfang Hospital of Southern Medical University. This observational study aims to create a comprehensive disease-specific cohort by recording clinical condition scales, lab results, and imaging data like X-rays and MRIs. The purpose is to build a rich database supporting future research projects, including large-scale and retrospective studies, without adding new treatments or tests beyond routine care. The study gathers two main datasets: one on SpA condition information and another on SpA imaging. The condition dataset includes disease duration, symptoms, family history, comorbidities, medication history, and disease activity scores like BASDAI and ASDASCRP. Quality of life and physical function are assessed using scales such as BASFI, EQ-5D, and SF-36. Lab tests recorded include CRP and ESR, but only if prescribed by the usual physician. Imaging data cover various MRIs, CT scans, ultrasounds, and X-rays related to SpA, with scores recorded when available. Participants either provide informed consent for prospective data collection during routine visits every 3 months for the first year and every 6 months for the next three years, totaling four years, or their retrospective data from prior visits are included without new consent if they no longer attend. Researchers monitor disease activity, quality of life, imaging findings, and adverse events throughout. Personal privacy is protected, and no additional interventions are introduced during the follow-up period.
CONDITIONS
Brief Title
Bidirectional Cohort Study of Nanfang Spondyloarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Attended Nanfang Hospital, Southern Medical University between 2010 and 2030
- For prospective cohort: voluntary participation with signed informed consent
- For retrospective cohort: patients from April 2010 to April 2024 who will not return for further visits are included without new consent; patients from May 2024 to April 2025 must provide consent
- Age between 10 and 59 years
- Diagnosed with spondyloarthritis according to 2009 ASAS axial or 2011 ASAS peripheral classification criteria
You will not qualify if you...
- Women who are pregnant, planning to become pregnant, or breastfeeding
- Moderate to severe heart failure (New York Heart Association Class 3 or 4)
- Active peptic ulcers or bleeding
- Considered unsuitable for participation by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for consent and eligibility assessment
Duration - Up to 4 years
Participants who undergo routine clinical care for spondyloarthritis are observed, with clinical data and imaging collected during their regular visits.
Visits every 3 months for the first year, then every 6 months for the following 3 years
Trial Site Locations
Total: 1 location
1
Nanfang Hostipal,Southern Medical University
Guangzhou, Guangdong, China, 510515
Actively Recruiting
Research Team
J
Jun Xiao, Dr
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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