Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07360392

BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia

Led by Amasya University · Updated on 2026-04-22

88

Participants Needed

1

Research Sites

58 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Biceps Femoris Short Head (BiFeS) block is a new fascial plane block technique targeting the sensory innervation of the posterolateral capsule of the knee while preserving motor function. The aim of this study is to evaluate the postoperative analgesic efficacy of the BiFeS block combined with the adductor canal block (ACB) in patients undergoing total knee arthroplasty, compared to ACB + iPACK block. The study is planned as a prospective, randomized, double-blind, parallel two-group trial. Patients will be randomized in a 1:1 ratio to receive ACB + iPACK (Group A) or ACB + BiFeS (Group B). Postoperative pain scores (VAS), opioid consumption, early mobilization, and quality of recovery (QoR-15) outcomes will be compared.

CONDITIONS

Official Title

BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for unilateral total knee arthroplasty
  • Classified as ASA physical status I-III
Not Eligible

You will not qualify if you...

  • Scheduled for revision arthroplasty or bilateral surgery
  • Allergy to local anesthetics or contraindication to regional blocks
  • Neurological disorders, peripheral neuropathy, or conditions affecting lower extremity muscle strength
  • Coagulopathy or receiving anticoagulant therapy
  • History of severe liver, kidney, or heart failure
  • Chronic opioid use or history of substance abuse
  • Patients experiencing intraoperative complications (e.g., excessive bleeding)
  • Cases in which adequate sensory blockade is not achieved after the block

AI-Screening

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Trial Site Locations

Total: 1 location

1

Amasya University Sabuncuoğlu Şerefeddin Training and Research Hospital

Amasya, Turkey (Türkiye), 05200

Actively Recruiting

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Research Team

B

Bülent M Çam, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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