Actively Recruiting
Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients
Led by Universitätsklinikum Hamburg-Eppendorf · Updated on 2025-02-13
20
Participants Needed
1
Research Sites
77 weeks
Total Duration
On this page
Sponsors
U
Universitätsklinikum Hamburg-Eppendorf
Lead Sponsor
T
Technical University of Twente
Collaborating Sponsor
AI-Summary
What this Trial Is About
Hand and arm function is often significantly impaired in stroke patients, making its recovery a primary goal in rehabilitative treatment. This study investigates the effects of bifocal transcranial alternating current stimulation (tACS) on the frontoparietal network in stroke patients during the subacute to chronic recovery phase. By using non-invasive brain stimulation, the study aims to modulate the neural network connectivity between the ipsilesional parietal and premotor cortices. Electroencephalography and kinematic data will be utilized to assess the impact of tACS on functional connectivity and its subsequent effect on motor function. The ultimate goal is to enhance functional coupling within these networks to promote motor function in stroke patients.
CONDITIONS
Official Title
Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First-ever clinical stroke
- Signed informed consent
- First-ever clinical ischemic stroke at least 3 months ago
- Stimulation areas (PMv and IPS) are unaffected
- Residual deficits in the upper limb
You will not qualify if you...
- Presence of additional neurological or psychiatric disorders
- Use of psychotropic medication
- Pregnancy or potential pregnancy in female participants
- Pacemakers, other stimulators, or medication pumps
- Claustrophobia
- Non-MRI-compatible metallic implants or foreign objects in the body
- Contraindications for transcranial alternating current stimulation (e.g., epilepsy, history of seizures, any type of pacemaker)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Neurology, University Medical Center Hamburg-Eppendorf
Hamburg, Germany, 20246
Actively Recruiting
Research Team
F
Fanny Quandt, Dr. med.
CONTACT
R
Robert Schulz, PD Dr. med.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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