Actively Recruiting
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Led by The University of Texas Health Science Center, Houston · Updated on 2025-12-17
120
Participants Needed
1
Research Sites
314 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center, Houston
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia. Schizophrenia patients with depressive symptoms will be exposed to rTMS to improve their symptoms.
CONDITIONS
Official Title
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female ages between ages 18-60 years.
- Ability to give written informed consent (age 18 or above).
- Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10.
- Score of Calgary depression scale for schizophrenia (CDSS) 65 3.
You will not qualify if you...
- Inability to sign informed consent.
- Any major medical illnesses that may affect normal brain functioning, such as stroke, repeated seizure, significant head trauma with cognitive sequela, CNS infection or tumor, or other significant brain neurological conditions.
- Significant alcohol or other drug use other than nicotine or marijuana dependence.
- Inability to refrain from using alcohol and/or marijuana 24 hours or more prior to experiments.
- Pregnancy, including women of child-bearing potential not using contraception who have missed a menstrual period, or positive pregnancy test.
- Inability to participate in MRI scanning due to metallic devices or objects, or declining MRI.
- Failed TMS safety questionnaire.
AI-Screening
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Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
A
Alina Siatka
CONTACT
X
Xiaoming Du, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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