Actively Recruiting
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
Led by Hartford Hospital · Updated on 2025-04-02
114
Participants Needed
1
Research Sites
196 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will be a single center, prospective triple blinded randomized controlled study, comparing the use of liposomal bupivacaine (Exparel) to regular bupivacaine with adjuncts in bilateral mid-abdominal transverse abdominis plane (TAP) blocks for patients undergoing laparoscopic colectomy procedures.
CONDITIONS
Official Title
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for elective laparoscopic colectomy surgery to be performed by one of the 4 colorectal surgeons in the study.
- English speaking patients
- Patients with American Society of Anesthesiology (ASA) physical status score I- IV
You will not qualify if you...
- Emergency laparoscopic colectomy surgery
- Patients with distant metastatic cancers (e.g. bone, lung, brain)
- Scheduled for multi organs resection surgery in addition to colectomy
- Patients with contraindications to TAP or RS blocks including anatomical abnormalities, previous surgical interventions limiting bilateral TAP blocks, or infection at injection site
- Current colostomies
- History of allergy to local anesthetics
- Coagulopathy or coagulation disorder or receiving antithrombotic medications contraindicating peripheral nerve blockade
- Weight less than 40 kg
- Taking long-acting opioid medication or on continuous opioid > 50 MME per day for at least 30 days within 90 days prior to surgery
- Chronic pain syndrome with recent preoperative consultation to chronic pain service
- Current substance abuse or history within 3 months including illicit drugs or excessive alcohol consumption
- Pregnant, nursing, or planning pregnancy during study or within 1 month postoperatively
- Refusal or lack of providing the study consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hartford Hospital
Hartford, Connecticut, United States, 06102
Actively Recruiting
Research Team
A
Aseel Walker, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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