Actively Recruiting

Phase Not Applicable
FEMALE
NCT07352761

Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy

Led by Alexandria University · Updated on 2026-01-20

60

Participants Needed

2

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt. • Al-Madina Women Hospital, A specialized hospital of Obstetrics and Gynecology, Alexandria, Egypt. Patient selection: women with uterine leiomyomata and planning for laparoscopic myomectomy will be assessed for eligibility then will be enrolled in the trial according to the following inclusion and exclusion criteria, after providing a written informed consent of participation. Outcome variables of the study: The primary outcome is intraoperative blood loss and the change in postoperative hemoglobin. The secondary outcomes of this study are the operative time of performing uterine arteries occlusion and the postoperative ovarian reserve.

CONDITIONS

Official Title

Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women with uterine fibroids causing abnormal uterine bleeding, infertility, or pressure symptoms on urinary or rectosigmoid areas
  • Fibroid size between 3 and 10 cm in diameter
  • Maximum of 3 fibroids
Not Eligible

You will not qualify if you...

  • Contraindication to pneumoperitoneum and laparoscopy
  • Body mass index over 30 kg/m2
  • History of midline abdominal incisions
  • History of prior ovarian surgery
  • Hormonal treatment in the last 3 months before surgery
  • Not a good candidate for myomectomy or better suited for hysterectomy (e.g., 4 or more fibroids, adenomyosis, recurrent fibroids after myomectomy)
  • Suspected endometrial cancer or leiomyosarcoma features on ultrasound or MRI
  • Submucous fibroids requiring hysteroscopic myomectomy alongside laparoscopic surgery

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria Univeristy

Alexandria, El-Shatby, Egypt, 21723

Actively Recruiting

2

• Al-Madina Women Hospital, A specialized hospital of Obstetrics and Gynecology, Alexandria, Egypt.

Alexandria, Smouha, Egypt

Actively Recruiting

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Research Team

A

Ahmed Shoukry, MD/PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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