Actively Recruiting
Bile Omics for Diagnosing Indeterminate Biliary Strictures
Led by Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2025-06-11
260
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
S
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor
E
Eastern Hepatobiliary Surgery Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The diagnosis of malignant biliary strictures remains a challenging aspect of biliary endoscopy. Molecular biological testing techniques based on bile have been reported to improve detection rates. However, whether the combination of bile-based omics studies and biliary brush cytology/biopsy can enhance diagnostic sensitivity has not yet been reported. This study aims to collect bile from patients with malignant biliary strictures, screen for molecular markers associated with biliary malignancies through multi-omics analysis, and subsequently validate these markers to establish a bile-based molecular diagnostic model.
CONDITIONS
Official Title
Bile Omics for Diagnosing Indeterminate Biliary Strictures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indeterminate biliary strictures
- Aged 18-90 years
- Underwent ERCP with biliary biopsy and/or brush cytology
You will not qualify if you...
- Coagulation disorders
- Pregnancy
- Malignancies of other organs unrelated to biliary strictures
- Declined participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China, China, 200080
Actively Recruiting
Research Team
X
Xiaobo Cai, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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