Actively Recruiting
Bimanual Motor Skill Learning in Acute Stroke
Led by University Hospital of Mont-Godinne · Updated on 2024-12-16
160
Participants Needed
2
Research Sites
284 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL. The goals of this project are: to determine the neural substrates critical to achieve proximal and distal bimanual motor skill learning (bim-MSkL) by specifying whether (sub)acute stroke to different brain areas (cortical and subcortical) induce specific deficits in bimanual and/or distal bim-MSkL, which behavioral components are involved in bim-MSkL, and whether damage to the motor, sensory and inter-hemispheric pathways specifically impairs proximal and/or distal bim-MSkL.
CONDITIONS
Official Title
Bimanual Motor Skill Learning in Acute Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute stroke less than 21 days old
- Age between 18 and 90 years
- Confirmed ischemic or hemorrhagic stroke lesion on brain imaging
- Healthy individuals aged 18 to 90 years (for control group)
You will not qualify if you...
- Contraindications to MRI such as non-MR-compatible pacemaker, implanted devices, pregnancy, or claustrophobia
- Difficulty understanding or executing commands
- Drug or alcohol abuse
- Severe aphasia or cognitive deficits interfering with the study
- Inability to complete tasks due to paralysis of the arm
- Multiple strokes, dementia, or psychiatric conditions
- History of previous stroke or relevant neurological deficit (for healthy controls)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
CHU UCL Namur
Yvoir, Namur, Belgium, 5530
Actively Recruiting
2
University Hospital CHU Dinant Godinne UCL
Yvoir, Belgium, 5530
Actively Recruiting
Research Team
Y
Yves Vandermeeren, MD, PhD
CONTACT
C
Coralie van Ravestyn, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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