Actively Recruiting
Arrhythmia and Conduction Disorders Toward Pathophysiology Based Treatment ADAPT Biobank
Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2024-01-25
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are collecting body materials and data from patients with or at risk of cardiac arrhythmias who have undergone or will undergo invasive or non-invasive treatments. The goal is to create a detailed collection of patient information to support research and improve understanding of the complex causes, varied clinical presentations, and outcomes of different arrhythmias. This effort aims to help identify patient subgroups for personalized treatment and prevention strategies. The study involves gathering bodily materials such as blood, left atrial appendage tissue, and various fat patches for biochemical marker assessments, histological, and molecular analyses related to cardiac arrhythmias. It includes patients participating in linked clinical trials and those undergoing cardiothoracic surgery. Different groups focus on specific types of arrhythmias, imaging studies, or tissue donations. Participants contribute clinical data and samples that are connected with their medical records for ongoing follow-up. Researchers monitor outcomes like new onset atrial fibrillation and recurrence of cardiac arrhythmia over a five-year period. The biobank supports long-term research by providing valuable materials and information to study the disease process and improve diagnosis, prevention, and treatment.
CONDITIONS
Brief Title
Biobank for "Arrhythmia and Conduction Disorders: TowArd Pathophysiology Based Treatment"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients visiting the AMC outpatient clinic
- Patients included in ongoing or future clinical trials linked to this biobank, including MARK AF, INDICO AF, PREDICT AF, WEIGHTLOSS AF, MAD AF
- Patients with cardiac arrhythmias such as supraventricular tachycardia (including atrial fibrillation, atrial tachycardia, atrial flutter, AVNRT, AVRT)
- Patients with ventricular tachycardia (including ventricular tachycardia, ventricular flutter, ventricular fibrillation)
- Patients with bradycardia (sinus node dysfunction, AV node dysfunction, interventricular conduction disorder)
- Patients with arrhythmogenic cardiomyopathies (dilated cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy)
You will not qualify if you...
- Age under 18 years
- Unable or unwilling to comply with study procedures
- Pregnancy or of childbearing potential without adequate contraception
- New York Heart Association (NYHA) class IV heart failure symptoms or left ventricular ejection fraction less than 35%
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At the time of cardiothoracic surgery or thoracoscopic atrial fibrillation ablation surgery
Participants provide bodily materials including blood and tissue samples for biochemical marker assessments and molecular analyses related to cardiac arrhythmias.
1 to 2 visits depending on surgery or procedure
Duration - Up to 5 years
Participants' clinical data and medical records are linked for longitudinal follow-up to study the course and outcomes of cardiac arrhythmias.
Follow-up visits aligned with routine clinical care
Trial Site Locations
Total: 1 location
1
Amsterdam University Medical Center location AMC
Amsterdam, Netherlands
Actively Recruiting
Research Team
E
Elise Hulsman, Bc RN
J
Joris de Groot, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
7
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