Actively Recruiting
Biobank for Cholestatic Liver Diseases.
Led by Mayo Clinic · Updated on 2026-02-17
9150
Participants Needed
1
Research Sites
1721 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).
CONDITIONS
Official Title
Biobank for Cholestatic Liver Diseases.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with PSC between 18 and 85 years old at enrollment
- Diagnosis of PSC based on standard criteria including clinical and biochemical evidence of chronic cholestasis for at least six months, positive cholangiographic findings, and compatible liver biopsies if available
- Patients with PSC who have had orthotopic liver transplantation can enroll except for bile collection
- Women with PSC of childbearing potential and pregnant women are eligible
- Patients diagnosed with PBC between 18 and 85 years old at enrollment
- Diagnosis of PBC based on standard criteria including clinical and biochemical evidence of chronic cholestasis for at least six months, positive anti-mitochondrial antibodies, and compatible liver biopsies if available
- Patients with PBC who have had orthotopic liver transplantation can enroll except for bile collection
- Women with PBC of childbearing potential and pregnant women are eligible
- Control participants without history of PBC, PSC, or other chronic liver disease between 18 and 85 years old
- Patients with other chronic liver diseases but no history of PBC or PSC between 18 and 85 years old
You will not qualify if you...
- PBC or PSC patients with known overlapping other chronic liver diseases
- Patients unable to provide informed consent
- Prisoners and institutionalized individuals
- Patients with PSC and orthotopic liver transplantation are excluded from bile collection during ERCP
- History of Roux en Y surgery excludes bile collection during ERCP
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic
Rochester, Minnesota, United States, 55901
Actively Recruiting
Research Team
E
Erik Schlicht, CCRP, B.A.
CONTACT
J
Jackie Bianchi
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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