Actively Recruiting
Biochemical, 2D and 3D Ultrasonographic Predictors of Pregnancy Outcome in Women With Threatened Abortion: A Prospective Cohort Study
Led by Cairo University · Updated on 2025-02-04
120
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how biochemical factors and ultrasound measurements can predict pregnancy outcomes in women experiencing threatened abortion during the first trimester. This prospective cohort study focuses on women aged 19 to 39 years with a single pregnancy between 6 and 11 weeks gestation, aiming to understand ongoing pregnancy rates at 12 weeks of gestational age. Participants undergo multiple ultrasound scans using 2D and 3D techniques. Initial assessments include crown-rump length, yolk sac diameter, gestational sac diameter, and embryonic heart rate measured by 2D ultrasound, alongside yolk sac volume measured by 3D ultrasound using the VOCAL method. These scans are performed at the start, then again after 1 to 2 weeks, and finally at the end of the 12th week of gestation. Throughout the study, women will be monitored with these ultrasound evaluations to track pregnancy progression. Researchers will analyze these measurements to assess their ability to predict pregnancy continuation. The study involves ongoing pregnancy rate assessment at 12 weeks and includes detailed imaging and biometric data collection at specified intervals.
CONDITIONS
Brief Title
Biochemical, 2D and 3D Ultrasonographic Predictors of Pregnancy Outcome in Women With Threatened Abortion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 19 to 39 years
- Body mass index (BMI) between 18 and 25 kg/m2
- Singleton pregnancy between 6 to 11 weeks gestation
- History of vaginal bleeding or spotting and/or abdominal pain with a live embryo seen on ultrasound
- Gestational age confirmed by last menstrual period and ultrasound crown-rump length measurement
You will not qualify if you...
- Uterine malformations or pathology such as submucous myoma
- Cervical abnormalities like polyps or severe chronic cervicitis
- Chronic medical conditions including uncontrolled diabetes or hypertension
- Smoking or drug abuse during this pregnancy
- Pregnancies from infertility treatments or assisted reproductive techniques
- Use of exogenous progesterone support
- Use of abortion induction drugs
- Diagnosed missed, incomplete, complete, anembryonic, or ectopic pregnancy by ultrasound
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Between 6 and 11 weeks of gestation
Participants undergo detailed ultrasound scans including 2D measurements of embryo and yolk sac, embryonic heart rate, and 3D ultrasound volume measurements to assess pregnancy status.
1 initial ultrasound visit
Duration - Up to the end of the first trimester
Participants have follow-up ultrasound scans one to two weeks later depending on their condition, and at the end of the first trimester to measure previously assessed parameters and monitor pregnancy outcome.
1 to 2 follow-up ultrasound visits
Trial Site Locations
Total: 1 location
1
Kasr Alainy medical school
Cairo, Egypt, 12111
Actively Recruiting
Research Team
A
Ahmed Maged
A
Ahmed chamel
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here