Biofeedback Training to Improve Vision in Children with Idiopathic Infantile Nystagmus Syndrome

What this Trial Is About

Researchers are studying Infantile Idiopathic Nystagmus (IIN), a common eye movement disorder in children that causes involuntary eye motions and can affect visual acuity and quality of life. This study aims to evaluate the effects of biofeedback training (BT), a new technique using microperimetry devices, on controlling eye movements and improving vision in children with IIN. The goal is to develop guidelines for using BT in nystagmus cases based on systematic assessment. Participants will be randomly assigned to one of two groups: one receiving active biofeedback training and the other receiving simulated (sham) training. The active BT sessions involve visual and audio feedback to help patients control their eye movements using a fixation target and training target, with four sessions lasting about 20 minutes each over four weeks. The simulated training includes a computer game-like task involving peripheral vision targets and is also conducted over four weekly sessions. Both groups receive take-home reading exercises to support the training. Throughout the study, children will undergo baseline assessments including distance and near vision tests, fixation stability, nystagmus amplitude, contrast sensitivity, stereopsis, and quality of life questionnaires. Follow-up visits occur one week and three months after training completion to measure changes in visual acuity, fixation stability, reading speed, and other vision-related outcomes. The study lasts up to 24 months, with careful monitoring for any discomfort or fatigue during training, although no significant risks are expected.

Biofeedback in Idiopathic Infantile Nystagmus Syndrome