Actively Recruiting
Biofilm Formation on Thoracic Drains: Clinical Significance and Association With Antibiotic Resistance
Led by Caner İşevi, MD · Updated on 2025-11-19
180
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the frequency and clinical importance of biofilm formation on chest drains used after thoracic surgery. Biofilms are bacterial communities that stick to surfaces and may lead to infections and antibiotic resistance. This observational study aims to understand how often biofilms form on chest drains and how they relate to factors like drain duration and infections after surgery. Participants are grouped based on how long their chest drains remain in place: 2 days or less, 3 to 4 days, and 5 days or longer. At the time of drain removal, small samples from the drain tips will be collected under sterile conditions and analyzed in the microbiology lab to detect biofilm presence, identify bacteria, and assess antibiotic resistance. Throughout the study, researchers will collect and analyze data on biofilm formation, bacterial growth, and resistance profiles. They will also examine how biofilms relate to postoperative infections and hospital stay length. The main measurement is the presence and intensity of biofilms on chest drain tips between 1 and 7 days after surgery, helping to improve drain management and infection prevention.
CONDITIONS
Brief Title
Biofilm on Chest Drains After Thoracic Surgery: Clinical Impact and Antibiotic Resistance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years and older
- Undergoing elective thoracic surgery requiring chest drain placement
- Able and willing to provide written informed consent
You will not qualify if you...
- Presence of active infection prior to surgery
- Emergency thoracic surgery
- Immunosuppressed patients (e.g., neutropenia, advanced malignancy, organ transplantation)
- Patients receiving systemic antibiotic therapy at the time of drain removal
- Drainage for empyema or pre-existing pleural infection
- Presence of extrathoracic infection focus
- Refusal or inability to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 7 days post-surgery
Participants who undergo routine thoracic surgery with chest drain placement are observed. Chest drain tips are collected at removal for microbiological and biofilm analysis.
1 visit (in-person) at time of chest drain removal
Trial Site Locations
Total: 1 location
1
Ondokuz Mayis University Medical Faculty, Department of Thoracic Surgery
Samsun, Samsun, Turkey (Türkiye), 55139
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here