Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT07021742

BioHealx® Anal Fistula Device Post Market Surveillance Study

Led by Signum Surgical USA Inc. · Updated on 2026-04-08

50

Participants Needed

5

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This post market surveillance study is a single arm multicenter study to demonstrate the long-term durability and effectiveness of the BioHealx Anal Fistula Device for fistula-in-ano closure (internal and external fistula openings).

CONDITIONS

Official Title

BioHealx® Anal Fistula Device Post Market Surveillance Study

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 - 75 years
  • Presence of Single Continuous Anal Fistula presenting for initial curative surgery
  • Failed or Recurrent Anal Fistula Closure
  • Minimum of 6-weeks of draining seton placed prior to procedure.
  • Availability for follow-up contacts and willingness to complete the Informed Consent.
Not Eligible

You will not qualify if you...

  • Fistula tract shorter than 2cm
  • Complex fistula tract (branching)
  • Body Mass Index > 35
  • Known uncontrolled diabetes or other systemic condition associated with impaired healing
  • Known HIV-positive or immunocompromised
  • Rectal prolapse
  • Pregnancy
  • Rectal / fistula malignancy
  • Crohn's disease
  • Ulcerative proctitis
  • Hidradenitis suppurativa of the anal region
  • Pilonidal sinus disease
  • Presence of hemorrhoid Involving fistula site
  • Continuous use of anti-inflammatory
  • Intersphincteric fistula in ano or fistula treatable by simple fistulotomy
  • Active infection or abscess involving fistula site
  • Known allergy to PLGA material
  • Any severe acute or uncontrolled chronic disease that according to the investigator might render the patient unsuitable for the study
  • Treatment with an investigational drug or medical device in the past 30 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

The Colorectal Institute

Fort Myers, Florida, United States, 33912

Actively Recruiting

2

Weill Cornell Medicine

New York, New York, United States, 10021

Actively Recruiting

3

Northwell Health

Staten Island, New York, United States, 10305

Actively Recruiting

4

Maininle Health Lankenau

Bryn Mawr, Pennsylvania, United States, 19010

Actively Recruiting

5

Geisinger

Danville, Pennsylvania, United States, 17822

Actively Recruiting

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Research Team

K

Katy Feeny

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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BioHealx® Anal Fistula Device Post Market Surveillance Study | DecenTrialz