Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07173426

Bioimpedance Integration for Optimized Fluid Management in Decompensated Heart Failure

Led by Mid and South Essex NHS Foundation Trust · Updated on 2025-09-15

255

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

Sponsors

M

Mid and South Essex NHS Foundation Trust

Lead Sponsor

A

Anglia Ruskin University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test whether using Bioimpedance Analysis (BIA) can help manage fluid levels in patients with heart failure who are admitted to the hospital with worsening symptoms. The main questions it aims to answer are: 1\. Does BIA-guided fluid management reduce the need for extra treatment (in the form of diuretics which helps remove excess fluid from the body) or re-hospitalization for heart failure within 90 days after discharge? Researchers will compare a group receiving BIA-guided treatment to a standard care group to see if BIA provides better results in managing fluid levels. Participants will be randomly assigned to one of two groups: BIA-Guided Treatment Group: Have BIA measurements done within 24 hours of admission and throughout their hospital stay to guide diuretic treatment. Standard Care Group: Have BIA measurements taken at admission and discharge, but the results will not be shared with the clinical team, who will manage fluid levels as usual. All patients will attend a follow-up visit in 2-4 weeks after discharge where the patient will undergo standard health checks, blood tests, and a questionnaire about how heart failure affects their quality of life. The investigators will then compare both groups for the primary outcome measure, which is the rates of rehospitalisation or need for additional decongestive treatment, within 90 days of discharge from hospital.

CONDITIONS

Official Title

Bioimpedance Integration for Optimized Fluid Management in Decompensated Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age >18 years
  • Hospitalized with a decompensated episode of Heart Failure regardless of Ejection Fraction
  • Able and willing to consent
Not Eligible

You will not qualify if you...

  • On a palliative care pathway and/or estimated life expectancy <3 months
  • Admitted to intensive care or on intensive care support
  • Currently participating in trials of new heart failure drugs or interventional treatments
  • Requiring Renal Replacement Therapy
  • Unable or unwilling to give consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

Basildon University Hospital

Basildon, Essex, United Kingdom, SS16 5NL

Actively Recruiting

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Research Team

H

Henry Oluwasefunmi Savage, MD FRCP

CONTACT

A

Archana Ganapathy, MRCP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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