Biological Bank Study for Adults with Autoimmune Cytopenia at a Specialized Reference Center

What this Trial Is About

Researchers are conducting an observational study to create a biological bank for patients with autoimmune cytopenia, including immune thrombocytopenia ITP, autoimmune hemolytic anemia AHA, autoimmune neutropenia, and erythroblastopenia. This research is a collaboration between clinical departments, biological resource centers, and research units such as CNRS and INSERM. It aims to support future translational and fundamental research to better understand these conditions and develop new treatments. The study involves collecting biological samples including 45 ml of whole blood to isolate peripheral blood mononuclear cells and monocytes, as well as 12 ml of urine. These samples will be used for basic research projects and might also be made available to the pharmaceutical industry to aid in the development of new molecules. The biological bank will support ongoing research into molecular mechanisms involved in platelet formation disorders and the role of regulatory CD8 T lymphocytes in autoimmune hemolytic anemia. Participants will provide informed consent and biological samples at the start of the study. Researchers will track the number of patients with autoimmune cytopenia who are newly diagnosed or under follow-up but not treated, using their biological samples for analysis. The study includes regular assessments as needed and will continue until 2027. Patient involvement includes sample donation and adherence to study procedures, with the goal of improving understanding and treatment options for autoimmune cytopenia.

Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia