Actively Recruiting

Age: 18Years +
All Genders
NCT06167369

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Led by Technische Universität Dresden · Updated on 2024-02-20

136

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to investigate biomarkers and neurocognitive markers of neurodegenerative processes in obstructive sleep apnea patients. The main questions the study aims to answer are: * Does neurodegeneration assessed by neurobiological markers and neurocognitive test performance exists in obstructive sleep apnea? * Are these neurodegenerative markers are associated with the adherence to clinical prescribed positive airway pressure therapy? Newly diagnosed patients with obstructive sleep apnea will be observed during the use of clinical prescribed positive pressure therapy. Different study related investigations take place before and six months after treatment start. Researchers will compare after six months the group of adherent treatment participants with the non-adherent treatment participants group to investigate if differences in the observed neurobiological or neurocognitive parameters exist.

CONDITIONS

Official Title

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newly diagnosed obstructive sleep apnea
  • Clinical indication for start of positive airway pressure therapy
  • Age older than 18 years
Not Eligible

You will not qualify if you...

  • Neurodegenerative disease
  • Multiple sclerosis
  • Stroke within last 3 months
  • Brain injury within last 3 months
  • MoCA less than 21 points
  • Higher degree chronic kidney disease (lower than 30 mL/min)
  • Regular use of sleep pills (e.g., Zopiclon, Mirtazapin, Daridorexant)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Technische Universität Dresden, Universitätsklinikum Dresden

Dresden, Saxony, Germany, 01307

Actively Recruiting

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Research Team

T

Tony Sehr, MD

CONTACT

M

Moritz D Brandt, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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