Study of Personalized Physical Activity to Improve Muscle Health in People Aged 60 and Over

What this Trial Is About

Researchers are studying how personalized physical activity affects muscle failure in elderly people. The study aims to identify biological markers related to muscle weakness and to tailor physical activity based on physical, biological, and psychosocial factors. It involves seniors who are healthy or frail, exploring differences in how individuals respond to exercise. Participants are randomly assigned to one of three groups 12 weeks of adapted and personalized physical activity, 12 weeks of generic adapted physical activity, or no physical activity. The study lasts five years with each participant involved for about three months. Physical activity programs and biological assessments are used to evaluate changes. During the study, participants undergo physical assessments including geriatric exams, gait analysis, bone density scans, and cognitive tests before and after the 12-week activity period. Blood samples are collected to study metabolomic and epigenetic signatures. Psychometric questionnaires assess personality, health perception, motivation, and attitudes toward aging. Researchers measure muscle power and other muscle function indicators to track improvements and differences among the groups.

Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity