Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
Healthy Volunteers
NCT05343286

Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity

Led by Centre Hospitalier Universitaire de Nice · Updated on 2025-12-03

900

Participants Needed

1

Research Sites

311 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Physical activity is one of the most effective therapeutic interventions for frailty, sarcopenia or dynapenia. The benefits of physical activity processes are already widely documented. Typically, researchers want to understand the average response to an intervention to determine its overall effectiveness. However, sports trainers have understood it for a long time, the response of an athlete or a patient to training is very variable and the standard deviations present in all the scientific studies on the subject confirm it. There is therefore inter-individual variation in the response to exercise, with some subjects showing much greater improvements than others. Thus, one can wonder if this "non-response" following training is specific to the training modality. The effects of physical exercise on the body depend mainly on its type, intensity and duration. Thus, from a practical point of view, the most important perspective is the prediction and, ultimately, the individual optimization of management through physical activity.

CONDITIONS

Official Title

Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than or equal to 60 years
  • Affiliated patient or beneficiary of a social security scheme
  • Patient having signed a prior informed consent.
Not Eligible

You will not qualify if you...

  • Neurocognitive disorder preventing the expression of informed consent
  • Patients protected by law under guardianship or curatorship, or who cannot participate in a clinical study under Article L. 1121-16 of the French Public Health Code
  • Presence of a physical or cognitive pathology preventing the performance of the adapted physical activity protocol over 3 months.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Nice

Nice, France, 06000

Actively Recruiting

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Research Team

O

Olivier GUERIN, PU-PH

CONTACT

F

Fréderic CHORIN, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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