Actively Recruiting
Biological Signatures Resulting From Occupational Exposure to Complex Mixtures of PAHs
Led by University Hospital, Grenoble · Updated on 2024-06-03
100
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research project aims at better understanding the early biological effects resulting from occupational exposure to complex Polycyclic Aromatic Hydrocarbon (PAH) mixtures. Current biomarkers used as part of biomonitoring campaigns are biomarkers of exposure, not numerous and poorly related to health effects. The aim of this study is thus to improve our understanding of biological consequences of such exposures, both in terms of proteins deregulation, metabolism deregulation and genotoxicity.
CONDITIONS
Official Title
Biological Signatures Resulting From Occupational Exposure to Complex Mixtures of PAHs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects aged 18 years or more
- Occupational exposure to PAHs for more than 3 months
- Signed informed consent
- Recruited by the occupational health service
You will not qualify if you...
- Obesity (BMI > 30)
- Having cancer or metabolic diseases (diabetes, dyslipidemia, amino-acid diseases, renal or hepatic impairment) at the start of the study
- Taking medications related to cancer or metabolic diseases at the start of the study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU Grenoble Alpes
Grenoble, France, 38043
Actively Recruiting
Research Team
R
Renaud PERSOONS, PhD, Pharm D
CONTACT
C
Christine DEMEILLIERS, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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