Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07024251

BIOlogical Waste Sample Collection for Progress in Oral and MAXillofacial Research

Led by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Updated on 2025-06-17

383

Participants Needed

1

Research Sites

258 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The BIO-MAX (BIOlogical waste sample collection for progress in oral and MAXillofacial research) study, led by IRCCS Ospedale Galeazzi-Sant'Ambrogio, is a five-year observational research project aimed at improving the understanding and treatment of oral and maxillofacial conditions. Researchers are collecting and analyzing biological samples-such as saliva, blood, and tissues typically discarded during dental and surgical procedures-from adult patients visiting the hospital for oral exams or surgery. A key focus is the study of salivary irisin, a promising biomarker linked to diseases like diabetes and heart disease. By examining how irisin levels vary with age, gender, lifestyle, and oral health, the team hopes to establish baseline values and better understand its diagnostic potential. In addition to irisin analysis, the study will explore other waste tissues to uncover disease mechanisms, identify new biomarkers, and test future therapies using patient-derived laboratory models. Overall, BIO-MAX seeks to enhance diagnostics, improve patient care, and pave the way for innovative treatments in oral and maxillofacial medicine.

CONDITIONS

Official Title

BIOlogical Waste Sample Collection for Progress in Oral and MAXillofacial Research

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female adults
  • 18 years old or older
  • Patients undergoing routine oral clinical examination or elective oral and maxillofacial surgery at IRCCS Ospedale Galeazzi - Sant'Ambrogio
Not Eligible

You will not qualify if you...

  • Younger than 18 years old
  • Unable to sign the Informed Consent
  • Positive for HIV, HCV, HBV, or TPHA if serological testing is required
  • Pregnant or breastfeeding with patient declaration

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Ospedale Galeazzi-Sant'Ambrogio

Milan, Italy, Italy, 20157

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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BIOlogical Waste Sample Collection for Progress in Oral and MAXillofacial Research | DecenTrialz