Study on Lung Cancer in Adults Diagnosed at Age 45 or Younger Including Non-Small Cell and Small Cell Lung Cancer Collecting Medical Data and Genetic Samples

What this Trial Is About

Researchers are studying lung cancer in adults aged 45 years or younger to better understand its causes, risks, and genetic changes. This study focuses on both non-small cell lung cancer NSCLC and small cell lung cancer SCLC, which are rare in this younger population. The goal is to improve screening and treatment options for young lung cancer patients by examining tumor and normal genetic alterations. Participants will provide access to their medical records, answer two short questionnaires, and give blood andor saliva samples. Optional participation includes providing tumor tissue samples or additional blood or tissue samples in the future. The study expects to enroll about 500 people and will continue until it closes or participants withdraw. During the study, researchers will collect data and specimens to build a repository over five years or until study closure. They will track genetic changes in tumors and germline samples to identify cancer-related alterations. Participants can expect to be involved through medical record reviews, brief surveys, and sample collections, with no treatment or intervention assigned by the study team.

Biology of Young Lung Cancer Study: The YOUNG LUNG Study