Actively Recruiting

Age: 40Years +
All Genders
NCT07109999

Biomarker-based Alzheimer's Disease Cohort Study (BASIC)

Led by Xuanwu Hospital, Beijing · Updated on 2025-08-07

2835

Participants Needed

1

Research Sites

1669 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study adopts a prospective cohort design, constructing a single-center cohort by recruiting patients with Alzheimer's disease (AD) who are positive for AD biomarkers. First, the investigators aim to establish a cohort of AD patients with positive biomarkers, thereby reserving suitable patient resources for future AD-related clinical trials. Second, based on the established cohort, the investigators will explore the associations between AD-related biomarkers and clinical manifestations among the elderly population in China, and identify potential risk factors influencing the progression of AD. Third, according to the identified risk factors for AD progression, the investigators will construct a risk early warning model for the progression rate of AD based on biomarkers, in order to achieve early identification and precise prevention and control of the progression risk of AD.

CONDITIONS

Official Title

Biomarker-based Alzheimer's Disease Cohort Study (BASIC)

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 40 years or older
  • Visiting Xuanwu Hospital, Capital Medical University
  • Meeting the core clinical diagnostic criteria for Alzheimer's disease-related mild cognitive impairment or probable AD according to the NIA-AA (2011)
  • Amyloid positivity confirmed by amyloid PET or cerebrospinal fluid biomarker tests
  • Providing informed consent
Not Eligible

You will not qualify if you...

  • Individuals unable to complete the assessment due to severe psychological or physiological disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xuanwu Hospital of Capital Medical University

Beijing, Beijing Municipality, China, 100053

Actively Recruiting

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Research Team

L

Liyang Liu

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Biomarker-based Alzheimer's Disease Cohort Study (BASIC) | DecenTrialz