Actively Recruiting
Biomarkers After Out-of-hospital Cardiac Arrest- a STEPCARE Substudy
Led by Region Skane · Updated on 2024-09-19
1000
Participants Needed
4
Research Sites
326 weeks
Total Duration
On this page
Sponsors
R
Region Skane
Lead Sponsor
U
University of Helsinki
Collaborating Sponsor
AI-Summary
What this Trial Is About
A prospective multicenter biomarker study with adult patients treated on intensive care units after out-of-hospital cardiac arrest. Patients will be recruited from specific sites participating in the Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation (STEPCARE) trial. (ClinicalTrials.gov ID NCT05564754). Blood samples will be collected at 12, 24, 48, and 72 hours after randomization in selected sites, aliquoted and frozen on-site. After trial completion, samples will be stored in a central biobank. Sample analysis will be performed in batch after trial completion. Functional outcome will be assessed at 30 days and 6 months after cardiac arrest.
CONDITIONS
Official Title
Biomarkers After Out-of-hospital Cardiac Arrest- a STEPCARE Substudy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- From sites participating in the STEPCARE biomarker substudy with out-of-hospital cardiac arrest
- Sustained return of spontaneous circulation (ROSC) defined as 20 minutes with signs of circulation without chest compressions
- Unconsciousness defined as inability to obey verbal commands or being intubated and sedated due to agitation after sustained ROSC
- Eligible for intensive care without restrictions or limitations
- Inclusion within 4 hours of sustained ROSC
You will not qualify if you...
- Receiving extracorporeal membrane oxygenation (ECMO) before randomization
- Pregnancy
- Suspected or confirmed intracranial hemorrhage
- Previously randomized in the STEPCARE trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Helsinki Hospital
Helsinki, Finland
Actively Recruiting
2
Helsingborgs Hospital
Helsingborg, Sweden
Actively Recruiting
3
Skåne university hospital
Lund, Sweden
Actively Recruiting
4
Skåne University Hospital
Malmö, Sweden
Actively Recruiting
Research Team
M
Marion Moseby-Knappe, MD, PhD
CONTACT
N
Niklas Nielsen, Prof, Principal Investigator
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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