Actively Recruiting
Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
Led by Roswell Park Cancer Institute · Updated on 2025-11-13
700
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates the clinical course of CDK4/6 inhibitor treated patients in the real-world setting among patients with breast cancer. CDK4/6 inhibitors may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Studying samples of blood, tissue, ascites or pleural effusions, and fresh body fluids or fresh biopsy, from patients with breast cancer that has spread to the other places in the body (metastatic) may help doctors learn more about cancer and the development of drug resistance in patients, and predict how well patients will respond to treatment.
CONDITIONS
Official Title
Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients with ER+/HER2- metastatic breast cancer or HR+/HER2- node positive, high-risk early breast cancer treated with CDK4/6 inhibitor-based therapies
- Includes patients receiving standard care or enrolled in non-interventional studies at Roswell Park or St. Vincent's Hospital
- Screening by review of patient medical records for current, past, or pending treatment with CDK4/6 inhibitor therapies
- Ability to understand the study and sign informed consent approved by an ethics committee or institutional review board
You will not qualify if you...
- Pregnant or nursing female subjects
- Unwilling or unable to follow study protocol requirements
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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