Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06836141

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

Led by Rush University Medical Center · Updated on 2025-08-08

118

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

R

Rush University Medical Center

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH

CONDITIONS

Official Title

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary Intracerebral Hemorrhage
  • Age 218 and < 80 years
Not Eligible

You will not qualify if you...

  • ICH score > 2
  • Pre-existing dementia
  • Prior history of stroke
  • Neurosurgical evacuation of hematoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rush University Medical Center

Chicago, Illinois, United States, 60614

Actively Recruiting

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Research Team

A

Amanda Sremac, BS

CONTACT

R

Rajeev Garg, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Biomarkers for Cognitive Decline in Intracerebral Hemorrhage | DecenTrialz