Actively Recruiting
Biomarkers and Imaging Markers for ICH
Led by Southwest Hospital, China · Updated on 2024-06-17
200
Participants Needed
1
Research Sites
673 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Intracerebral hemorrhage (ICH) is a subtype of stroke associated with high mortality and disability. Basic and clinical research has contributed to our understanding of the complex pathophysiology in ICH. However, questions regarding acute diagnosis, therapeutic decisions, and prognostication of ICH remain unanswered. Molecular biomarkers and imaging markers have revolutionalized diagnosis and treatment of many diseases, such as troponin use in myocardial infarction and magnetic resonance imaging (MRI) scan in ischemic stroke. Therefore, the investigators aim to discovery the potential biomarkers by screening samples of blood, cerebral spinal fluid, urine, saliva, and even tissues (if available) from ICH patients, and imaging markers via serial multimodality imaging scans such as computed tomography(CT), magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), positron emission tomography (PET), etc. These molecular and imaging markers would assist in contributing additional information to current tools for onset warning, diagnosis, therapy monitoring, risk stratification, intervention and prognosis for ICH patients.
CONDITIONS
Official Title
Biomarkers and Imaging Markers for ICH
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged 18-80 years
- Hematoma size is more than 5 ml
- Evidence of a spontaneous intracerebral hemorrhage on CT scan
- Patient within 72 hours of stroke onset
- Glasgow Coma Scale score between 5 and 15
- History of hypertension
You will not qualify if you...
- Individuals younger than 18 years or older than 80 years
- Hemorrhage caused by aneurysm, arteriovenous malformation, or other cerebrovascular diseases
- Intracerebral hemorrhage due to tumor or trauma
- Effects of previous anticoagulants not fully reversed
- Severe heart, lung, kidney, liver, autoimmune, or other organ diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Neurosurgery , Southwest Hospital, Third Military Medical University,
Chongqing, Chongqing Municipality, China, 400038
Actively Recruiting
Research Team
R
Rong Hu, Ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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