Actively Recruiting
Biomarkers for Invasive Mucormycosis
Led by University Hospital, Lille · Updated on 2025-12-26
100
Participants Needed
1
Research Sites
135 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Lille
Lead Sponsor
P
Plateforme PAGés, Analyses Glycoconjugués
Collaborating Sponsor
AI-Summary
What this Trial Is About
Mucormycosis (MM) is one of the main invasive fungal infection (IFI), and is determined by filamentous fungi belonging to the order of Mucorales, with a mortality rate ranging from 20 to 60% according to localization. Prompt initiation of adequate antifungal therapy is critical for treating mucormycosis. Early diagnostic is therefore essential. The presence in the Mucorales' cell wall of uncommon monosaccharides open interesting perspectives for the development of specific diagnostic biomarkers. This study evaluate a diagnostic test for mucormycosis in a cohort of patients with MM and in control groups (high-risk patients without MM and patients with another IFI).
CONDITIONS
Official Title
Biomarkers for Invasive Mucormycosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women
- Age between 3 and 64 years (18 to 64 years for control groups)
- Participants or guardians have given informed consent after receiving study information
- Participant has health insurance
- For case group: hospitalized patients diagnosed with mucormycosis by mycology, PCR, or pathology with compatible clinical signs
- For control group 1: patients at risk for invasive fungal infection undergoing hematopoietic stem cell transplant assessment but without ongoing infection
- For control group 2: patients diagnosed with disseminated candidiasis or invasive pulmonary aspergillosis based on established criteria
You will not qualify if you...
- Participants who do not meet the inclusion criteria
- Patients with co-infection of mucormycosis and another invasive fungal infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Lille
Lille, Hauts-de-France, France, 59000
Actively Recruiting
Research Team
M
Marjorie CORNU, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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