Actively Recruiting

Age: 18Years +
All Genders
NCT06353191

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Led by Mayo Clinic · Updated on 2026-02-27

1000

Participants Needed

4

Research Sites

660 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.

CONDITIONS

Official Title

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Treated for any malignancy with any type of chemotherapy including oral, parenteral therapy and immunotherapy
  • Diagnosed with cardiotoxicity such as cardiomyopathy, symptomatic heart failure, asymptomatic reduced systolic function, acute coronary syndrome, myocardial infarction, critical limb ischemia, cardiac arrhythmias or myocarditis possibly related to prior cancer treatment
  • Completed chemotherapy with no cardiotoxicity at least two years post treatment
  • Patients with cancer who will be starting systemic therapy with potentially cardiotoxic medications including chemotherapy, immunotherapy, or targeted therapy
  • Understanding of the protocol and its requirements, risks, and discomforts
  • Ability and willingness to sign an informed consent
Not Eligible

You will not qualify if you...

  • Inability to understand the informed consent or comply with the study protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259

Actively Recruiting

2

Mayo Clinic in Florida

Jacksonville, Florida, United States, 32224-9980

Actively Recruiting

3

Moffitt Cancer Center

Tampa, Florida, United States, 33612

Actively Recruiting

4

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Suspended

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Research Team

C

Clinical Trials Referral Office

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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