Actively Recruiting

Age: 18Years +
All Genders
NCT05117125

Biomarkers for Ventilator-associated Pneumonia

Led by Region Skane · Updated on 2024-11-15

1000

Participants Needed

5

Research Sites

376 weeks

Total Duration

On this page

Sponsors

R

Region Skane

Lead Sponsor

L

Lund University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate different peptide biomarkers, variations in the microbiome and patterns in the bacterial transcriptome as prognostic or diagnostic biomarkers of VAP.

CONDITIONS

Official Title

Biomarkers for Ventilator-associated Pneumonia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Admission to an intensive care unit
  • Intubation within last 24 hours
  • Anticipated mechanical ventilation of at least 48 hours
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Fraction of inspired oxygen (FiO2) above 70% or positive end-expiratory pressure (PEEP) above 15
  • Severe coagulopathy defined as spontaneous PK(INR) >1.8 or thrombocytes <50
  • Ongoing lung infection at ICU admission
  • Severely elevated or unstable intracranial pressure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Vestre Viken

Drammen, Norway, 3004

Actively Recruiting

2

Hospital de São Francisco Xavier

Lisbon, Portugal

Actively Recruiting

3

Skåne University Hospital, Dept. of Infectious diseases

Lund, Sweden

Actively Recruiting

4

Skåne university Hospital, ICU

Malmö, Sweden

Actively Recruiting

5

Karolinska University Hospital, ICU

Solna, Sweden

Not Yet Recruiting

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Research Team

M

Magnus Paulsson, PhD MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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