Actively Recruiting

Age: 18Years +
All Genders
NCT03142074

Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-01

180

Participants Needed

1

Research Sites

465 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

An aortic aneurysm (thoracic or abdominal) is a permanent dilatation of the aorta caused by weakening in the arterial wall. The feared complication is aortic rupture or dissection, leading to potentially lethal aortic bleeding and associated with mortality rates up to 95%. The current diagnosis criteria do not suffice, therefore the goal of this study is the development of an improved biomechanics-based and microstructural-based diagnostic tool.

CONDITIONS

Official Title

Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients suffering from thoracic aortic aneurysms (ATAA), asymptomatic or symptomatic.
  • Patients with ruptured ATAA undergoing an emergency surgery.
  • Signed informed consent.
Not Eligible

You will not qualify if you...

  • Patients with ruptured ATAA due to trauma.
  • Presence of any aneurysm feature preventing collection of tissue samples suitable for biomechanical and microstructural studies.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UZ Leuven

Leuven, Vlaams Brabant, Belgium, 3000

Actively Recruiting

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Research Team

N

Nele Famaey, PhD

CONTACT

A

Amber Hendrickx, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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