Actively Recruiting
Biomechanical and Morphological Characterization of PTTD
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2025-04-15
100
Participants Needed
1
Research Sites
310 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Posterior tibial tendon dysfunction (PTTD) is a progressive condition of the tendon of the tibialis posterior muscle with symptoms of tendinopathy or even rupture. Functionally, it is associated with the inability to lock the mid foot and thus manifests itself as a main contributor to adult acquired flatfoot deformity. Concerning treatment, clinical decision making is currently based on a classification integrating various parameters as pain, flexibility of the foot joints, the condition of the posterior tibial tendon assessed through ultrasound imaging and radiographic assessment of arthritic changes. Surprisingly, this classification does not consider any morphologic characteristics (the shape of a bone or joint) or functional, biomechanical characteristics of the foot and ankle, i.e. based on kinematics (e.g. range of motion) and/or kinetics (center of pressure, angular velocity, moment, power absorption and power generation of a joint). Detailed biomechanical characteristics of the foot and ankle can be reliably collected by instrumented gait analysis wherein a 3D camera system is combined with a force plate and plantar pressure platform. Kinematic studies in the field of PTTD typically considered the foot as a structure consisting of three segments: hind foot, forefoot and hallux. Consequently, the mid foot segment (the Chopart and Lisfranc joints) has been neglected, although it is this segment that is particularly affected in PTTD patients. The aim of this research is to overcome the limitations of the current classification system and treatment of PTTD patients, by complementing the current standard-of-care clinical assessment with better insight in the pathologic changes that occur in PTTD patients.
CONDITIONS
Official Title
Biomechanical and Morphological Characterization of PTTD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with posterior tibial tendon dysfunction at any clinical stage
- Age between 18 and 75 years
- Signed informed consent form
- Control group participants with no foot or ankle pain or pathology
- Control group age between 18 and 75 years
- Control group signed informed consent form
You will not qualify if you...
- Younger than 18 years old
- Unable to walk without mobility aids
- Unable to walk less than 100 meters
- Leg length difference greater than 3 cm
- Body mass index (BMI) over 30 kg/m²
- Unable to perform gait analysis
- Any medical condition affecting normal gait
- Pregnant at the start or during the study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
S
Sander Wuite
CONTACT
K
Kevin Deschamps
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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