Actively Recruiting
Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)
Led by University Hospitals, Leicester · Updated on 2023-11-29
9500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University Hospitals, Leicester
Lead Sponsor
U
University of Leicester
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying cardiovascular diseases in both hospital patients and healthy community volunteers to better understand diagnosis and predict outcomes. The cardiovascular conditions include coronary artery disease, heart failure, heart attacks, valve disease, cardiac surgery, arrhythmias, aneurysms, embolism, strokes, peripheral vascular disease, and hypertension. Current diagnostic methods may lack accuracy, so this research aims to collect detailed clinical information and biological samples to explore disease mechanisms and improve patient care. The study is observational and planned to last for 20 years. Participants include patients with various cardiovascular diseases as well as healthy volunteers without cardiovascular or other diseases. The study involves collecting physiological measurements, patient questionnaires, blood, and urine samples to analyze proteins, chemicals, and genetic biomarkers. These data will help examine disease mechanisms and improve predictions of treatment responses and future clinical events. There is no intervention or treatment given, as this is an observational study. During the study, participants will undergo assessments including clinical evaluations and sample collections. Researchers will monitor biomarkers over time to understand disease progression and treatment effects. The primary outcome is to enhance knowledge of cardiovascular disease mechanisms over 20 years, with secondary outcomes focusing on predicting responses to treatments based on biological markers. Participation involves regular data collection and follow-up, contributing to long-term cardiovascular research.
CONDITIONS
Brief Title
Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All outpatients and inpatients with cardiovascular disease, of either gender
- Aged 18-90 years old
- Conditions include coronary artery disease, heart failure, heart attacks, valve disease, cardiac surgery, dysrhythmias, aneurysms, embolism, strokes, peripheral vascular disease, hypertension, or chest pain
- Healthy volunteers aged 18-90 years old from the community without cardiovascular or other diseases
You will not qualify if you...
- Unable to give consent
- Non-cardiovascular illness likely to cause death within 6 months
- Known infection with HIV, Hepatitis B, or other infection risks from unfixed material
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 20 years
Participants undergo physiological measurements, complete patient-reported questionnaires, and provide blood samples to improve understanding of cardiovascular disease mechanisms and treatment responses.
Periodic visits over the course of the study
Trial Site Locations
Total: 1 location
1
University Hospitals Leicester
Leicester, United Kingdom
Actively Recruiting
Research Team
E
Emma P Beeston
T
Tara Maitland
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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