Actively Recruiting
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
Led by Zhongshan Ophthalmic Center, Sun Yat-sen University · Updated on 2025-12-12
300
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma. Minimally invasive glaucoma surgery, particularly angle surgery, has advanced recently, allowing clear visualization of angle structures like the trabecular meshwork and Schlemm's canal using surgical goniolens. Techniques for angle intervention include widening the angle, reopening closed angles, and rebuilding outflow pathways using methods such as laser peripheral iridotomy, Argon laser peripheral iridoplasty, and mechanical separation of adhered tissues. Our research team plans to conduct imaging studies to track the healing of angle tissues post-surgery, aiming to support innovation and standardization of minimally invasive angle surgery.
CONDITIONS
Official Title
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Glaucoma patients eligible for standalone or combined angle intervention surgeries such as LPI, LPIP, goniosynechialysis, trabeculotomy alone or with surgical iridectomy or phacoemulsification and intraocular lens implantation
- Patients able to undergo preoperative exams including CASIA2-OCT, ultrasound biomicroscopy, slit-lamp gonioscopy, and optical biometry
- Patients willing to sign informed consent and follow-up according to the study protocol
You will not qualify if you...
- Patients with severe eye conditions like corneal infection, ulcer, trauma, tumors, retinal vascular occlusion, or retinal detachment
- Patients with eye diseases affecting ocular measurements or visual field exams
- Long-term local or systemic use of glucocorticoids
- Patients with severe systemic diseases
- Pregnant or lactating women
- Unable to complete 12-month postoperative follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongshan ophthalmic center
Guangzhou, Guangdong, China, 51006dddddd0
Actively Recruiting
Research Team
X
Xinbo Gao, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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