Collection of Data and Samples from People Aged 3 to 100 Years with Allergic, Sinus, or Atopic Diseases Long-Term Follow-Up to Study Allergy and Immune Disorders

What this Trial Is About

Researchers are gathering information and biological samples from people aged 3 to 100 years who have allergic or sinus diseases, such as asthma, eczema, pollen allergies, and other related conditions. This study aims to build a repository of clinical, laboratory, and diagnostic data to better understand these diseases and support future research. Participants include those with suspected or confirmed allergic and atopic disorders evaluated by allergist-immunologists and rhinologists. Participants will visit the NIH Clinical Center for clinical evaluation and sample collection, including blood, skin swabs, nasal brushings, nasal fluid, and urine. Some may have allergy skin prick tests and lung function tests. Additional tissue samples may be gathered during routine medical procedures if applicable. Visits occur at baseline, annually, and at the end of the study over 1 to 3 years, with some telehealth visits and the option to send in samples. During the study, participants complete questionnaires about their symptoms and health. Researchers collect and store data and samples for future medical research. The study tracks clinical and diagnostic information over time, but no experimental treatments are provided. The total participation period spans 1 to 3 years, with ongoing evaluation and monitoring at scheduled visits.

A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up