Research Registry for Inflammatory and Invasive Breast Cancer Collecting Medical Data and Tissue Samples to Support Future Treatment Studies

What this Trial Is About

Researchers are studying patients with inflammatory or invasive breast cancer to create a research tissue registry by collecting medical data and biospecimens. This study focuses on gathering tissue, blood, and stool samples along with clinical and imaging information from patients newly diagnosed or highly suspected of having inflammatory breast cancer. The goal is to help doctors better understand and treat inflammatory breast cancer through laboratory research. Participants will provide tissue samples including primary tumor, lymph node metastases, or distant metastases before systemic therapy or surgery when applicable. Samples of serum, plasma, whole blood, oral swabs, skin and stool bacterial cultures are also collected for microbiome analysis. Additionally, patients complete questionnaires and interviews lasting about 30 minutes. The study includes patients newly diagnosed as well as those previously diagnosed who are seeking further treatment. During the study, participants undergo medical data collection, blood draws, tissue and stool sample collection, and complete interviews and questionnaires. Researchers will follow sample and data collection for up to 2 years to analyze changes and correlate findings to treatment and toxicity. This observational study is led by M.D. Anderson Cancer Center and involves no experimental treatment, focusing on data and biospecimen gathering to support future breast cancer research.

Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer