Actively Recruiting
Inflammatory Breast Cancer (IBC) Registry: Collecting Biospecimens and Medical Data for Research
Led by M.D. Anderson Cancer Center · Updated on 2026-04-15
1200
Participants Needed
10
Research Sites
N/A
Total Duration
On this page
Sponsors
M
M.D. Anderson Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying patients with inflammatory or invasive breast cancer to create a research tissue registry by collecting medical data and biospecimens. This study focuses on gathering tissue, blood, and stool samples along with clinical and imaging information from patients newly diagnosed or highly suspected of having inflammatory breast cancer. The goal is to help doctors better understand and treat inflammatory breast cancer through laboratory research. Participants will provide tissue samples including primary tumor, lymph node metastases, or distant metastases before systemic therapy or surgery when applicable. Samples of serum, plasma, whole blood, oral swabs, skin and stool bacterial cultures are also collected for microbiome analysis. Additionally, patients complete questionnaires and interviews lasting about 30 minutes. The study includes patients newly diagnosed as well as those previously diagnosed who are seeking further treatment. During the study, participants undergo medical data collection, blood draws, tissue and stool sample collection, and complete interviews and questionnaires. Researchers will follow sample and data collection for up to 2 years to analyze changes and correlate findings to treatment and toxicity. This observational study is led by M.D. Anderson Cancer Center and involves no experimental treatment, focusing on data and biospecimen gathering to support future breast cancer research.
CONDITIONS
Brief Title
Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with clinical diagnosis of primary inflammatory breast cancer (IBC), second primary IBC, or highly suspicious for IBC (MD Anderson patients only)
- Histological diagnosis of invasive breast cancer, or highly suspicious for IBC (pending diagnosis at MD Anderson only)
- Newly diagnosed or highly suspicious for IBC, or have paraffin blocks or unstained slides from initial diagnosis or mastectomy (MD Anderson patients only)
- Age over 18 years
- Able to provide informed consent
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 2 years
Participants undergo collection of medical data, blood, tissue, and stool samples, and complete questionnaires and interviews to provide information and biospecimens for research purposes.
1 to 2 visits depending on sample collection and assessments
Trial Site Locations
Total: 10 locations
1
Banner - MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
Actively Recruiting
2
Scripps - MD Anderson Cancer Center
La Jolla, California, United States, 92037
Active, Not Recruiting
3
Banner - MD Anderson Cancer Center - Northern Colorado
Greeley, Colorado, United States, 80631
Actively Recruiting
4
Baptist - MD Anderson Cancer Center
Jacksonville, Florida, United States, 32207
Actively Recruiting
5
Covenant Medical Center
Saginaw, Michigan, United States, 48604
Active, Not Recruiting
6
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
7
MD Anderson in Katy
Houston, Texas, United States, 77094
Actively Recruiting
8
MD Anderson League City
Nassau Bay, Texas, United States, 77058
Actively Recruiting
9
MD Anderson in Sugar Land
Sugar Land, Texas, United States, 77478
Actively Recruiting
10
MD Anderson in The Woodlands
The Woodlands, Texas, United States, 77384
Actively Recruiting
Research Team
J
Jie Willey
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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