Chronic ankle instability is associated with proprioception deficits: A systematic review and meta-analysis.
Xiao'ao Xue, Tengjia Ma, Qianru Li...
https://pubmed.ncbi.nlm.nih.gov/33017672Actively Recruiting
Led by Istanbul University - Cerrahpasa · Updated on 2025-03-24
40
Participants Needed
1
Research Sites
17 weeks
Total Duration
I
Istanbul University - Cerrahpasa
Lead Sponsor
B
Bezmialem Vakif University
Collaborating Sponsor
Ankle sprains are common musculoskeletal injuries, making up 15-30% of such cases. Many patients experience repeated ankle sprains after an initial injury, and inadequate treatment can lead to chronic ankle instability (CAI) in 30-70% of cases. This research aims to compare the effects of unipedal versus bipedal exercise programs in early rehabilitation for people with CAI, focusing on pain, functional stability, fear avoidance, disease severity, and patient satisfaction. Participants diagnosed with CAI will be randomly assigned to one of two exercise groups: an early bipedal exercise group or a late bipedal exercise group. Both groups will receive supervised proprioceptive, resistive, neuromuscular exercises, and stretching guided by a physiotherapist twice a week for 8 weeks. The early group will use both limbs actively during the first four weeks, while the late group will do so during the last four weeks. Throughout the 24-week study, participants will be assessed for pain using the Visual Analog Scale, functional performance with the Single Leg Hop Test, and fear avoidance with the Tampa Kinesiophobia Scale at multiple time points. Additional measures include ankle instability, joint motion, foot and ankle ability, balance tests, and overall change ratings. Researchers will monitor progress and satisfaction to understand which exercise timing better supports recovery and function in CAI.
CONDITIONS
Bipedal vs. Unipedal Exercises in Chronic Ankle Instability
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants undergo supervised proprioceptive, resistive, neuromuscular exercises and stretching under the guidance of a physiotherapist. Exercises are performed twice a week for 8 weeks, with early or late bipedal exercise timing depending on group assignment.
2 visits per week for 8 weeks
Duration - 24 weeks
Participants are assessed for recovery and functional outcomes through various tests and questionnaires over 24 weeks following treatment.
3 visits for assessments over 24 weeks
Total: 1 location
1
Acibadem Mehmet Ali Aydinlar University
Istanbul, Turkey (Türkiye), 34752
Actively Recruiting
A
Ayşenur Erekdağ, MSc
S
Sezen Karabörklü Argut, PhD
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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