Study of Bipolar Radio-frequency Ablation After Failed Standard Unipolar Ablation for Ventricular Arrhythmias at the Base of the Heart

What this Trial Is About

Researchers are studying ventricular arrhythmias VA that originate at the base of the heart, focusing on cases where the standard unipolar radio-frequency RF ablation treatment fails. This study aims to find out how many patients need a follow-up procedure using bipolar RF ablation, which may be more effective for difficult-to-reach arrhythmias. They also want to identify electrophysiological signals that predict success or failure of these ablation methods and assess how these treatments affect patients quality of life. The study involves patients who have already undergone unipolar ablation for VA but may require further treatment. If unipolar ablation does not succeed, patients may receive bipolar ablation, which uses two electrodes to deliver RF energy between adjacent heart structures for deeper tissue treatment. The procedures use advanced mapping and catheter systems to guide ablation. Patients are monitored during the procedures, and coronary angiography is performed to ensure safety. Both unipolar and bipolar ablations are evaluated for their immediate and one-month effectiveness. Participants will have detailed heart studies and electrophysiological tests to guide treatment. They will be assessed before and after ablation with Holter ECG monitoring and quality of life questionnaires. Researchers are measuring the need for bipolar ablation after failed unipolar treatment, how well specific heart signals predict success, and the impact of ablation on symptoms and life quality over two years. Follow-up includes clinical evaluations and tests to track arrhythmia recurrence and treatment outcomes.

Bipolar Radio-frequency Ablation After Standard Unipolar Approach - Prospective Registry.