Actively Recruiting
BIS Variability and Change in Quality of Recovery After Surgery
Led by Sakarya University · Updated on 2026-04-08
126
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective observational study aims to examine the relationship between fluctuations in anesthesia depth, measured by bispectral index (BIS) monitoring during surgery, and changes in patients' postoperative recovery quality. BIS monitoring is routinely used during general anesthesia to assess the depth of anesthesia, but BIS values often fluctuate over time rather than remaining stable. The clinical significance of this variability is not well understood. In this study, BIS variability during anesthesia induction and maintenance will be evaluated and compared with changes in postoperative recovery quality. Recovery quality will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire, which will be administered before surgery and again on the first postoperative day. The primary outcome of the study will be the change in QoR-15 score from the preoperative baseline to postoperative day one (ΔQoR-15). Delirium screening and routine perioperative clinical data will also be collected. No additional interventions beyond standard anesthesia care will be performed. The results of this study may help improve understanding of how intraoperative anesthesia stability relates to patient recovery after surgery.
CONDITIONS
Official Title
BIS Variability and Change in Quality of Recovery After Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years
- Scheduled for elective laparoscopic cholecystectomy
- American Society of Anesthesiologists (ASA) physical status I-III
- Planned general anesthesia with routine bispectral index (BIS) monitoring
- Ability to provide written informed consent
You will not qualify if you...
- History of neurological disease
- Use of neuropsychiatric medications
- Cognitive impairment or mental retardation
- Inability to complete the Quality of Recovery-15 (QoR-15) questionnaire
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Sakarya University Training and Research Hospital, Department of Anesthesiology and Reanimation
Sakarya, Serdivan, Turkey (Türkiye), 54000
Actively Recruiting
Research Team
A
Ahmet R Doğan, M.D
CONTACT
A
Ayça Taş Tuna, Prof. Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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