Actively Recruiting
Bite Force Measurements
Led by Rutgers, The State University of New Jersey · Updated on 2025-07-24
112
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
Sponsors
R
Rutgers, The State University of New Jersey
Lead Sponsor
N
New Jersey Alliance for Clinical and Translational Science
Collaborating Sponsor
AI-Summary
What this Trial Is About
ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids. Addressing the need for non-opioid pain alternatives is crucial. Emerging evidence suggests that dental pain from pulpal and periodontal conditions (affecting the tooth's nerve and surrounding tissues) involves neuropathic mechanisms, such as mechanical allodynia (MA) and central sensitization (CS). These mechanisms can amplify pain perception, causing typically non-painful actions, like chewing, to become painful and resulting in hypersensitivity extending beyond the affected tooth. Reliably identifying these mechanisms with quantitative measures can support improved pain assessment and targeted non-opioid treatment. This minimally invasive prospective cohort study will use the FDA-approved Innobyte® device, a precise bite-force measurement tool, to evaluate periodontal health and to quantify mechanical pain thresholds in patients requiring endodontic treatment (root canal therapy).
CONDITIONS
Official Title
Bite Force Measurements
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals presenting for a lower 1st or 2nd molar filling in a healthy tooth without nerve infection, increased mobility from gum disease, or prior root canal treatment on a lower molar
- Individuals presenting for a lower molar root canal treatment
- 18 years or older
- Capable of providing informed consent
- Opposing tooth present, symptom-free, and with adequate structure to make contact during biting
- English-speaking
You will not qualify if you...
- Compromised ability to protect their interests, such as prisoners, children, pregnant women, or patients with intellectual/cognitive disability
- Taking prescription pain medications for long-standing health conditions
- Addiction or substance dependence
- Swelling extending beyond the tooth in question
- Currently taking antibiotics for infection or swelling
- Missing the complementary molar on the same or opposite side of the mouth
- Missing more than 2 teeth in a quadrant (excluding third molars)
- Any molar in the pair or on the opposite side is painful to biting pressure or tapping with a mouth mirror
- Taken any pain medication within the last 6 hours
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Rutgers School of Dental Medicine
Newark, New Jersey, United States, 07103
Actively Recruiting
Research Team
G
Gayathri D Subramanian, PhD, DMD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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